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KMID : 0356920070530030356
Korean Journal of Anesthesiology
2007 Volume.53 No. 3 p.356 ~ p.360
Comparison of Thiopental Sodium and Ketamine Induction on Emergence Agitation after Desflurane Anesthesia in Children undergoing a Tonsillectomy
Kim Han-Seok

Lee Soo-Kyung
Kang Hyo-Seok
Kim Young-Mi
Choi Hyun
Moon Hyun-Soo
Abstract
Backgrounds: It is widely known that desflurane provides fast emergence but with a high incidence of emergence agitation. This study was designed to investigate the emergence agitation resulting from thiopental or ketamine induction with desflurane anesthesia for pediatric patients.

Methods: Forty patients, aged 3£­8 years, scheduled for a tonsillectomy or a tonsillectomy and adenoidectomy were randomly allocated into two groups. Anesthesia was induced using 5 mg/kg thiopental sodium (Group T patients) or 2 mg/kg ketamine (Group K patients), and was maintained using O2-N2O-desflurane. The recovery time and incidence of emergence agitation were assessed.

Results: The incidence of emergence agitation was less in patients in the ketamine induction group. There were no differences in the recovery time and reported side effects.

Conclusions: We conclude that ketamine induction provides less emergence agitation when compared to thiopental induction for desflurane anesthesia for a pediatric tonsillectomy or a tonsillectomy and adenoidectomy without delayed recovery. (Korean J Anesthesiol 2007; 53: 356¡­60)
KEYWORD
desflurane, emergence agitation, ketamine, thiopental
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